The load-transfer method (t-z method) is easy to calculate and can be used in design practice. The most important thing of using the t-z method is the determination of the load-transfer parameters. The uncertainties of the two parameters in the hyperbolic load-transfer function of pile foundation were investigated. Data of seven static load tests with strain gauges, twelve static load tests without strain gauges together with 75 load tests at a single site in Shanghai were collected. Statistical analyses were conducted for both measured and back-calculated parameters for different soil layers. It was found that the uncertainties of the back-calculated values are close to those of the measured ones. The parameters a and b are negatively correlated. Compared with basic soil properties such as unit weight and shear strength parameters, the COVs of the load transfer parameters are greater. According to the Kolmogorov-Smirnov (K-S) test at a significance level of 5%, the normal distribution for both parameters can not be rejected.