Journal of Shanghai Jiaotong University ›› 2020, Vol. 54 ›› Issue (8): 785-791.doi: 10.16183/j.cnki.jsjtu.2019.068

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Optimization Design of Flexible Neural Electrodes Based on Orthogonal Experimental Method

XIE Jie, ZHANG Wenguang(), YIN Xuele, LI Wei   

  1. State Key Laboratory of Mechanical System and Vibration, Shanghai Jiao Tong University, Shanghai 200240, China
  • Received:2019-03-14 Online:2020-08-28 Published:2020-08-18
  • Contact: ZHANG Wenguang


In order to optimize the design of flexible neural electrodes, three parameters of elastic modulus, electrode thickness, and wedge angle are comprehensively studied. The experimental groups are established based on orthogonal experimental design. The maximum strain of brain tissue in different experimental groups are evaluated by ANSYS. In addition, a new hybrid flexible electrode is designed based on the stimulation results. The experimental results reveal that when elastic modulus is 8.5GPa, thickness is 15μm and wedge angle is 45°, the maximum strain of brain tissue due to micromotion is the smallest, i.e., 5.5627×10-2. Moreover, a sandwich-type hybrid flexible neural electrode is designed with an elastic modulus of 8.5GPa on both sides and an elastic modulus of 5.5GPa in the intermediate layer. The sandwich-type structure can effectively reduce micromotion damage and implant deformation compared to the traditional electrode.

Key words: flexible electrode, finite element, orthogonal experiment, optimized design

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