Review on the Interlimb Neural Coupling and Its Potential Usage in Walking Rehabilitation

doi:10.1007/s12204-014-1541-3

Abstract

Abstract: Human performs bipedal gait with synchronized arm swing. Apart from the observation that arm movement during gait is the outcome of a mechanical and energetic optimization, the synergetic upper and lower limb movement during gait is a neutrally coordinated motor output, that is, the interlimb movement is neutrally coupled. Patients with injuries to the central nervous system demonstrate the interlimb neural coupling. Researches on central pattern generator and the reflex studies reveal that the interlimb neural coupling is a quadrupedal heritage. Based on the theory of the interlimb neural coupling, both the upper and lower limbs should be practiced synchronously during regular gait training to promote walking rehabilitation for patients with gait disorders. Further development of a gait robotic system with synchronized arm swing is required to test the clinical application of the neural coupling in gait restoration.

Key words: interlimb neural coupling| quadripedal heritage| gait rehabilitation

摘要： Human performs bipedal gait with synchronized arm swing. Apart from the observation that arm movement during gait is the outcome of a mechanical and energetic optimization, the synergetic upper and lower limb movement during gait is a neutrally coordinated motor output, that is, the interlimb movement is neutrally coupled. Patients with injuries to the central nervous system demonstrate the interlimb neural coupling. Researches on central pattern generator and the reflex studies reveal that the interlimb neural coupling is a quadrupedal heritage. Based on the theory of the interlimb neural coupling, both the upper and lower limbs should be practiced synchronously during regular gait training to promote walking rehabilitation for patients with gait disorders. Further development of a gait robotic system with synchronized arm swing is required to test the clinical application of the neural coupling in gait restoration.

关键词: interlimb neural coupling| quadripedal heritage| gait rehabilitation

CLC Number:

R 496

FANG Juan (方娟), XIE Le (谢叻), YANG Guo-yuan* (杨国源). Review on the Interlimb Neural Coupling and Its Potential Usage in Walking Rehabilitation[J]. Journal of shanghai Jiaotong University (Science), 2014, 19(5): 561-564.

References

[1] Meyns P, Bruijn S M, Duysens J. The how and why of arm swing during human walking [J]. Gait & Posture, 2013, 38: 555-562.
[2] Ortega J D, Fehlman L A, Farley C T. Effects of aging and arm swing on the metabolic cost of stability in human walking [J]. Journal of Biomechanics, 2008, 41(16): 3303-3308.
[3] Pontzer H, Holloway J H, Raichlen D A, et al.Control and function of arm swing in human walking and running [J]. The Journal of Experimental Biology,2009, 212: 523-534.
[4] Collins S H, Adamczyk P G, Kuo A D. Dynamic arm swinging in human walking [J]. Proceedings of the Royal Society B: Biological Sciences, 2009, 76: 3679-3688.
[5] Kuhtz-Buschbeck J P, Jing B. Activity of upper limb muscles during human walking [J]. Journal of Electromyography and Kinesiology, 2012, 22: 199-206.
[6] Donker S F, Mulder T, Nienhuis B, et al. Adaptations in arm movements for added mass to wrist or ankle during walking [J]. Experimental Brain Research,2002, 145: 26-31.
[7] Maclellan M J, Qaderdan K, Koehestanie P,et al. Arm movements during split-belt walking reveal predominant patterns of interlimb coupling [J]. Human Movement Science, 2013, 32: 79-90.
[8] Dietz V, Fouad K, Bastiaanse C M. Neuronal coordination of arm and leg movements during human locomotion[J]. European Journal of Neuroscience, 2001,14: 1906-1914.
[9] Huang H J, Ferris D P. Neural coupling between upper and lower limbs during recumbent stepping [J].Journal of Applied Physiology, 2004, 97: 1299-1308.
[10] Bovonsunthonchai S, Hiengkaew V,Vachalathiti R, et al. Effect of speed on the upper and contralateral lower limb coordination during gait in individuals with stroke [J]. The Kaohsiung Journal of Medical Sciences, 2012, 28: 667-672.
[11] Stephenson J L, Lamontagne A, de Serres S J.The coordination of upper and lower limb movements during gait in healthy and stroke individuals [J]. Gait & Posture, 2009, 29: 11-16.
[12] Kawashima N, Nozaki D, Abe M O, et al. Shaping appropriate locomotive motor output through interlimb neural pathway within spinal cord in humans [J].Journal of Neurophysiology, 2008, 99: 2946-2955.
[13] Meyns P, van Gestel L, Bruijn S M, et al. Is interlimb coordination during walking preserved in children with cerebral palsy? [J]. Research in Developmental Disabilities, 2012, 33: 1418-1428.
[14] Meyns P, Molenaers G, Desloovere K, et al. Interlimb coordination during forward walking is largely preserved in backward walking in children with cerebral palsy [J]. Clinical Neurophysiology, 2013, 125(3):552-561.
[15] Dietz V. Do human bipeds use quadrupedal coordination?[J]. Trends in Neurosciences, 2002, 25(9): 462-467.
[16] Forssberg H, Grillner S, Halbertsma J. The locomotion of the low spinal cat. I. Coordination within a hindlimb [J]. Acta Physiologica Scandinavica, 1980,108(3): 269-281.
[17] Yang J F, Stephens M J, Vishram R. Infant stepping:A method to study the sensory control of human walking [J]. Journal of Physiology, 1998, 507(3): 927-937.
[18] Zehr E P, Duysens J. Regulation of arm and leg movement during human locomotion [J]. The Neuroscientist,2004, 10(4): 347-361.
[19] Forssberg H, Grillner S, Rossignol S. Phase dependent reflex reversal during walking in chronic spinalcats [J]. Brain Research, 1975, 85: 103-107.
[20] Drew T, Rossignol S. A kinematic and electromyographic study of cutaneous reflexes evoked from the forelimb of unrestrained walking cats [J]. Journal of Neurophysiology, 1987, 57: 1160-1184.
[21] Duysens J, Trippel M, Horstmann G A, et al.Gating and reversal of reflexes in ankle muscles during human walking [J]. Experimental Brain Research, 1990,82: 351-358.
[22] Yang J F, Stein R B. Phase-dependent reflex reversal in human leg muscles during walking [J]. Journal of Neurophysiology, 1990, 63(5): 1109-1117.
[23] Zehr E P, Kido A. Neural control of rhythmic, cyclical human arm movement: Task dependency, nerve specificity and phase modulation of cutaneous reflexes[J]. Journal of Physiology, 2001, 537(3): 1033-1045.
[24] Raineteau O, Schwab M E. Plasticity of motor systems after incomplete spinal cord injury [J]. Nature Reviews Neuroscience, 2001, 2: 263-273.
[25] Barbeau H, Wainberg M, Finch L. Description and application of a system for locomotor rehabilitation [J]. Medical and Biological Engineering and Computing,1987, 25: 341-344.
[26] Eke-Okoro S T, Gregoric M, Larsson L E. Alterations in gait resulting from deliberate changes of arm-swing amplitude and phase [J]. Clinical Biomechanics,1997, 12(F8): 516-521.
[27] Ford M P, Wagenaar R C, Newell K M. Arm constraint and walking in healthy adults [J]. Gait & Posture, 2007, 26: 135-141.
[28] Behrman A L, Harkema S J. Locomotor training after human spinal cord injury: A series of case studies[J]. Physical Therapy, 2000, 80(7): 688-700.
[29] de Kam D, Rijken H, Manintveld T, et al. Arm movements can increase leg muscle activity during submaximal recumbent stepping in neurologically intact individuals [J]. Journal of Applied Physiology, 2013,115: 34-42.
[30] Zehr E P, Loadman P M, Hundza S R. Neural control of rhythmic arm cycling after stroke [J]. Journal of Neurophysiology, 2012, 108: 891-905.