基于9.4 T磁共振测速的门静脉血流动力学与数值模拟

doi:10.1007/s12204-024-2764-6

摘要/Abstract

摘要： 门静脉狭窄是儿童肝移植术后常见的并发症之一。准确的血流动力学评估对肝移植术后的并发症风险预测至关重要。为了预测肝移植术后门静脉血栓的形成位置，使用商业软件MIMICS从CT图像来重建单出口和三出口血管模型并采用9.4 T磁共振成像扫描仪测量速度场。基于磁共振测速仪的实验数据，对计算流体动力学结果进行了验证，研究两个门静脉模型的壁面压力和剪应力。仿真结果可用于门静脉肝移植术后早期血栓形成的临床预测。

关键词: 磁共振成像，血流动力学，计算流体力学，门静脉血栓

Abstract: Portal vein stenosis is one of the common complications after liver transplantation in children. Accurate hemodynamic assessment is crucial for predicting the risk of complications after liver transplantation. In order to predict the location of portal vein thrombosis after liver transplantation surgery, single-outlet and three-outlet vascular models were reconstructed from computed tomography images by commercial software MIMICS. The velocity field was measured using a 9.4T magnetic resonance imaging scanner. Based on the experiment data of magnetic resonance velocimetry, computational fluid dynamics was verified, validated and then used to study the pressure and shear stresses on the wall of the two portal vein models. The simulation results can serve for the clinical prediction of early thrombosis after liver transplantation in portal vein.

Key words: magnetic resonance imaging, hemodynamics, computational fluid dynamics, portal venous thrombosis

中图分类号:

. 基于9.4 T磁共振测速的门静脉血流动力学与数值模拟[J]. J Shanghai Jiaotong Univ Sci, 2025, 30(4): 768-777.

Li Jianing, Zong Zhipeng, Zhou Tao, Zhang Jiang, Ma Haiteng. Hemodynamics in Portal Venous Based on 9.4T Magnetic Resonance Velocimetry and Numerical Simulations[J]. J Shanghai Jiaotong Univ Sci, 2025, 30(4): 768-777.

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