Abstract: Using the modified twofluid (MTF) model, the flow and heat transfer of air curtain and air around were simulated. Moreover, the air leakage quantity of the open vertical display cases was also confirmed. Using the results calculated by the MTF model as the testing and validation data, the optimized function was solved by adaptive support vector machine (ASVM) algorithm. By the validated experimental data, the defrosting water quantity and TEC/TDA of optimum display case are reduced by 39.2% and 19.3% respectively, which reduces the air leakage significantly.