Medicine-Engineering Interdisciplinary

Short-Term Effects of Ambient Air Pollutants on Outpatient Visits for Childhood Allergic Diseases in Shanghai, China

  • HU Yi1 (户宜) ,
  • GU Jianlei1 (顾坚磊) ,
  • WU Dan1 (吴丹) ,
  • WANG Xiaolei2 (王晓雷) ,
  • LU Hui ¨ 1 ,
  • 2 (吕晖) ,
  • YU Guangjun1 ,
  • 3? (于广军)
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  • (1. Center for Biomedical Informatics, Shanghai Children’s Hospital, Shanghai Jiao Tong University School of Medicine,Shanghai 200040, China; 2. SJTU-Yale Joint Center for Biostatistics and Data Science, Department of Bioinformatics and Biostatistics, Shanghai Jiao Tong University, Shanghai 200240, China; 3. Shanghai Engineering Research Center for Big Data in Pediatric Precision Medicine, Shanghai 200040, China)

Accepted date: 2021-08-04

  Online published: 2024-11-28

Abstract

This study aims to investigate the short-term effects of ambient air pollutants on outpatient visits for childhood allergic diseases. Daily data on ambient air pollutants (NO2, SO2, CO and PM2.5) and outpatient visits for childhood allergic diseases (asthma, atopic dermatitis and allergic rhinitis) were obtained in Shanghai, China from 2013 to 2014. The effects of ambient air pollutants were estimated for total outpatient visits for childhood allergic diseases, gender and age stratification and disease classification by using distributed lag non-linear model (DLNM). We found positive associations between short-term exposure to air pollutants and childhood allergic diseases. Girls and children aged  7 years old were more likely to be sensitive to ambient air pollutants. NO2 and SO2 showed stronger effects on asthma and atopic dermatitis, respectively. This study provides evidence that short-term exposure to ambient air pollutants can increase the risk of childhood allergic diseases.

Cite this article

HU Yi1 (户宜) , GU Jianlei1 (顾坚磊) , WU Dan1 (吴丹) , WANG Xiaolei2 (王晓雷) , LU Hui ¨ 1 , 2 (吕晖) , YU Guangjun1 , 3? (于广军) . Short-Term Effects of Ambient Air Pollutants on Outpatient Visits for Childhood Allergic Diseases in Shanghai, China[J]. Journal of Shanghai Jiaotong University(Science), 2024 , 29(6) : 979 -994 . DOI: 10.1007/s12204-022-2454-1

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