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Journal of Shanghai Jiaotong University(Science) >

2023 , Vol. 28 >Issue 4: 546

DOI: https://doi.org/10.1007/s12204-022-2424-7

Medicine-Engineering Interdisciplinary Research

Gas Exchange Mechanism of High Frequency Ventilation: A Brief Narrative Review and Prospect

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  • (1. School of Mechanical and Electrical Engineering, Hunan City University, Yiyang 413099, Hunan, China; 2. Department of Respiratory Medicine, Shanghai Chest Hospital, Shanghai 200030, China; 3. Hunan Micomme Medical Technology Development Co., Ltd., Changsha 410205, China)

Received date: 2021-01-28

  Accepted date: 2021-06-30

  Online published: 2023-07-31

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Abstract

The high frequency ventilation (HFV) can well support the breathing of respiratory patient with 20%—40% of normal tidal volume. Now as a therapy of rescue ventilation when conversional ventilation failed, the HFV has been applied in the treatments of severe patients with acute respiratory failure (ARF), acute respiratory distress syndrome (ARDS), etc. However, the gas exchange mechanism (GEM) of HFV is still not fully understood by researchers. In this paper, the GEM of HFV is reviewed to track the studies in the last decades and prospect for the next likely studies. And inspired by previous studies, the GEM of HFV is suggested to be continually developed with various hypotheses which will be testified in simulation, experiment and clinic trail. One of the significant measures is to study the GEM of HFV under the cross-disciplinary integration of medicine and engineering. Fully understanding the GEM can theoretically support and expand the applications of HFV, and is helpful in investigating the potential indications and contraindications of HFV.

Key words： mechanical ventilation, high frequency ventilation, gas exchange mechanisms

Cite this article

YUAN Yueyang1* (袁越阳)，CHEN Yuqing2 (陈宇清)，ZHOU Lil(周理), LIU Wei3 (刘炜)， DAI Zheng3(戴 征) . Gas Exchange Mechanism of High Frequency Ventilation: A Brief Narrative Review and Prospect[J]. Journal of Shanghai Jiaotong University(Science), 2023 , 28(4) : 546 . DOI: 10.1007/s12204-022-2424-7

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