[1] EDSBERG L E, BLACK J M, GOLDBERG M, et al.Revised national pressure ulcer advisory panel pressureinjury staging system [J]. Journal of Wound, Ostomy& Continence Nursing, 2016, 43(6): 585-597.
[2] BLACK J, BAHARESTANI M M, CUDDIGAN J, etal. National Pressure Ulcer Advisory Panel’s updatedpressure ulcer staging system [J]. Advances in Skin &Wound Care, 2007, 20(5): 269-274.
[3] PRESTON A, RAO A, STRAUSS R, et al. Deep tissue pressure injury: A clinical review [J]. The American Journal of Nursing, 2017, 117(5): 50-57.
[4] BOUTEN C V, KNIGHT M M, LEE D A, et al. Compressive deformation and damage of muscle cell subpopulations in a model system [J]. Annals of Biomedical Engineering, 2001, 29(2): 153-163.
[5] CEELEN K K, STEKELENBURG A, LOERAKKERS, et al. Compression-induced damage and internal tissue strains are related [J]. Journal of Biomechanics,2008, 41(16): 3399-3404.
[6] MAK A F T, ZHANG M, TAM E W C. Biomechanics of pressure ulcer in body tissues interacting with external forces during locomotion [J]. Annual Review of Biomedical Engineering, 2010, 12: 29-53.
[7] BADER D L, BARNHILL R L, RYAN T J. Effect of externally applied skin surface forces on tissue vasculature [J]. Archives of Physical Medicine and Rehabilitation, 1986, 67(11): 807-811.
[8] JAN Y K, BRIENZA D M, BONINGER M L, et al.Comparison of skin perfusion response with alternating and constant pressures in people with spinal cord injury [J]. Spinal Cord, 2011, 49(1): 136-141.
[9] MANORAMA A, MEYER R, WISEMAN R, et al.Quantifying the effects of external shear loads on arterial and venous blood flow: Implications for pressureulcer development [J]. Clinical Biomechanics, 2013,28(5): 574-578.
[10] TAYLOR R, JAMES T. The role of oxidative stress in the development and persistence of pressure ulcers [M]//Pressure ulcer research. Berlin, Heidelberg:Springer, 2005: 205-232.
[11] MILLER G E, SEALE J L. The recovery of terminallymph flow following occlusion [J]. Journal of Biomechanical Engineering, 1987, 109(1): 48-54.
[12] SCHUBERT V, FAGRELL B. Evaluation of the dynamic cutaneous post-ischaemic hyperaemia and thermal response in elderly subjects and in an area at riskfor pressure sores [J]. Clinical Physiology, 1991, 11(2):169-182.
[13] JAUL E, BARRON J, ROSENZWEIG J P, et al.An overview of co-morbidities and the development of pressure ulcers among older adults [J]. BMC Geriatrics, 2018, 18(1): 305.
[14] SULLIVAN R. A two-year retrospective review of suspected deep tissue injury evolution in adult acute care patients? [J]. Ostomy/Wound Management, 2013,59(9): 30-39.
[15] FLETCHER J, BADER D, DOWNIE F, et al. Recognising, managing and preventing deep tissue injury(DTI) [M]//London: Wounds UK, 2017.
[16] BLACK J M, CUDDIGAN J E, WALKO M A, et al.Medical device related pressure ulcers in hospitalized patients [J]. International Wound Journal, 2010, 7(5):358-365.
[17] VANGILDER C, MACFARLANE G D, HARRISONP, et al. The demographics of suspected deep tissue injury in the United States: An analysis of the International Pressure Ulcer Prevalence Survey 2006-2009[J]. Advances in Skin & Wound Care, 2010, 23(6): 254-261.
[18] COX J, EDSBERG L E, KOLOMS K, et al. Pressure injuries in critical care patients in US hospitals:Results of the international pressure ulcer prevalence survey [J]. Journal of Wound, Ostomy, and Continence Nursing, 2022, 49(1): 21-28.
[19] MAO C L, RIVET A J, SIDORA T, et al. Update on pressure ulcer management and deep tissue injury[J]. The Annals of Pharmacotherapy, 2010, 44(2): 325-332.
[20] National Pressure Ulcer Advisory Panel, European Pressure Ulcer Advisory Panel, Pan Pacific PressureInjury Alliance. Prevention and treatment of pressure ulcers: Quick reference guide [M]//2nd ed. Perth:Cambridge Media, 2014: 1-75.
[21] KUMAR S. Seats, seating, and seat selection: Implications for pressure ulcers [M]//Ergonomics for rehabilitation professionals. Boca Raton: CRC Press,2009: 232-259.
[22] HENSON A, KENNEDY-MALONE L. A quality improvement project comparing two treatments for deep tissue pressure injuries to feet and lower legs of longterm care residents [J]. Advances in Skin & WoundCare, 2020, 33(11): 594-598.
[23] HONAKER J, BROCKOPP D, MOE K. Suspected deep tissue injury profile: A pilot study [J]. Advancesin Skin & Wound Care, 2014, 27(3): 133-140.
[24] SUN W N, LIU Y Q, SHENG L S, et al. Clinical nursing practice of three cases of deep tissue injury [J].Chinese Journal of Injury Repair and Wound Healing (Electronic Edition), 2020, 15(2): 156-158 (inChinese).
[25] MATSUMOTO M, NAKAGAMI G, KITAMURA A,et al. Ultrasound assessment of deep tissue on thewound bed and periwound skin: A classification system using ultrasound images [J]. Journal of Tissue Viability, 2021, 30(1): 28-35.
[26] QUINTAVALLE P R, LYDER C H, MERTZ P J, et al.Use of high-resolution, high-frequency diagnostic ultrasound to investigate the pathogenesis of pressure ulcer development [J]. Advances in Skin & Wound Care,2006, 19(9): 498-505.
[27] TANG L L, SHEN X, GONG S J, et al. Application ofultrasound in early diagnosis of deep tissue injury andprediction of prognosis of pressure ulcers [J]. Nursingand Rehabilitation Journal, 2017, 16(11): 1193-1196(in Chinese).
[28] LIU Q F, LI L J, JI L H, et al. Feasibility study onpressure ulcer management using high-frequency ultrasound by ward medical staff [J]. Chinese NursingResearch, 2019, 33(1): 166-169 (in Chinese).
[29] KANNO N, NAKAMURA T, YAMANAKA M, etal. Low-echoic lesions underneath the skin in subjectswith spinal-cord injury [J]. Spinal Cord, 2009, 47(3):225-229.
[30] HELVIG E I, NICHOLS L W. Use of high-frequencyultrasound to detect heel pressure injury in elders [J].Journal of Wound, Ostomy, and Continence Nursing,2012, 39(5): 500-508.
[31] PORTER-ARMSTRONG A P, ADAMS C,MOORHEAD A S, et al. Do high frequency ultrasound images support clinical skin assessment? [J].ISRN Nursing, 2013, 2013: 314248.
[32] SCAFIDE K N, NARAYAN M C, ARUNDEL L. Bedside technologies to enhance the early detection ofpressure injuries: A systematic review [J]. Journalof Wound, Ostomy, and Continence Nursing, 2020,47(2): 128-136.
[33] AOI N, YOSHIMURA K, KADONO T, et al. Ultrasound assessment of deep tissue injury in pressure ulcers: Possible prediction of pressure ulcer progression[J]. Plastic and Reconstructive Surgery, 2009, 124(2):540-550.
[34] DEPREZ J F, BRUSSEAU E, FROMAGEAU J, et al.On the potential of ultrasound elastography for pressure ulcer early detection [J]. Medical Physics, 2011,38(4): 1943-1950.
[35] HAMALUIK K, MOUSSA W, FERGUSON-PELL M.Numerical characterization of quasi-static ultrasoundelastography for the detection of deep tissue injuries[J]. IEEE Transactions on Medical Imaging, 2014,33(7): 1410-1421.
[36] SCH?FER G, DOBOS G, LüNNEMANN L, et al.Using ultrasound elastography to monitor human softtissue behaviour during prolonged loading: A clinicalexplorative study [J]. Journal of Tissue Viability, 2015,24(4): 165-172.
[37] MANSUR R, PEKO L, SHABSHIN N, et al. Ultrasound elastography reveals the relation between bodyposture and soft-tissue stiffness which is relevant to theetiology of sitting-acquired pressure ulcers [J]. Physiological Measurement, 2021, 41(12): 124002.
[38] YABUNAKA K, IIZAKA S, NAKAGAMI G, et al.Three-dimensional ultrasound imaging of the pressureulcer. A case report [J]. Medical Ultrasonography, 2015,17(3): 404-406.CHEN J L, GUO R Q, ZHOU Q, et al. Teaching practice and exploration of standardized training for resident doctors of ultrasound department [J]. Journal ofClinical Ultrasound in Medicine, 2018, 20(5): 355-356(in Chinese).
[40] MOORE Z, PATTON D, RHODES S L, et al. Subepidermal moisture (SEM) and bioimpedance: A literature review of a novel method for early detection ofpressure-induced tissue damage (pressure ulcers) [J].International Wound Journal, 2017, 14(2): 331-337.
[41] CHING C T S, CHOU M Y, JIANG S J, et al. Tissue electrical properties monitoring for the preventionof pressure sore [J]. Prosthetics and Orthotics International, 2011, 35(4): 386-394.
[42] CARMO-ARA′UJO E M, DAL-PAI-SILVA M, DALPAI V, et al. Ischaemia and reperfusion effects on skeletal muscle tissue: Morphological and histochemicalstudies [J]. International Journal of ExperimentalPathology, 2007, 88(3): 147-154.
[43] ZHANG G Z, YU J, ZHU H B. Research progresson relationship between subepidermal moisture andpressure injury [J]. Chinese Nursing Research, 2021,35(22): 4043-4045 (in Chinese).
[44] PARK S, KIM C G, KO J W. The use of sub-epidermalmoisture measurement in predicting blanching erythema in jaundice patients [J]. Journal of Wound Care,2018, 27(5): 342-349.
[45] OLIVEIRA A L, MOORE Z, CONNOR T O, et al.Accuracy of ultrasound, thermography and subepidermal moisture in predicting pressure ulcers: A systematic review [J]. Journal of Wound Care, 2017, 26(5):199-215.
[46] BATES-JENSEN B M, MCCREATH H E,NAKAGAMI G, et al. Subepidermal moisturedetection of heel pressure injury: The pressure ulcerdetection study outcomes [J]. International WoundJournal, 2018, 15(2): 297-309.
[47] BATES-JENSEN B M, MCCREATH H E,PONGQUAN V. Subepidermal moisture is associated with early pressure ulcer damage in nursinghome residents with dark skin tones: Pilot findings [J].Journal of Wound, Ostomy, and Continence Nursing,2009, 36(3): 277-284.
[48] GEFEN A, GERSHON S. An observational, prospective cohort pilot study to compare the use of subepidermal moisture measurements versus ultrasound and visual skin assessments for early detection of pressureinjury [J]. Ostomy/Wound Management, 2018, 64(9):12-27.
[49] BATES-JENSEN B M, REILLY S, HILLIARD C, et al. Subepidermal moisture and pressure injury in a pediatric population: A prospective observational study[J]. Journal of Wound, Ostomy, and Continence Nursing, 2020, 47(4): 329-335.
[50] KIM C G, PARK S, KO J W, et al. The relationshipof subepidermal moisture and early stage pressure injury by visual skin assessment [J]. Journal of Tissue Viability, 2018, 27(3): 130-134.
[51] BATES-JENSEN B M, MCCREATH H E, KONO A,et al. Subepidermal moisture predicts erythema andstage 1 pressure ulcers in nursing home residents: A pilot study [J]. Journal of the American Geriatrics Society, 2007, 55(8): 1199-1205.
[52] O’BRIEN G, MOORE Z, PATTON D, et al. The relationship between nurses assessment of early pressureulcer damage and sub epidermal moisture measurement: A prospective explorative study [J]. Journal ofTissue Viability, 2018, 27(4): 232-237.
[53] OKONKWO H, BRYANT R, MILNE J, et al. Ablinded clinical study using a subepidermal moisturebiocapacitance measurement device for early detectionof pressure injuries [J]. Wound Repair and Regeneration, 2020, 28(3): 364-374.
[54] GERSHON S. Using subepidermal moisture level as anindicator of early pressure damage to local skin and tissue [J]. Advances in Skin & Wound Care, 2020, 33(9):469-475.
[55] UETA M, SUGAMA J, KONYA C, et al. Use of ultrasound in assessment of necrotic tissue in pressure ulcers with adjacent undermining [J]. Journal of Wound Care, 2011, 20(11): 503-504.
[56] GEFEN A. The SEM Scanner for early pressure ulcerdetection: A 360-degree review of the technology [J].Wounds International, 2020, 11(4): 22-30.
[57] BRYANT R A, MOORE Z E, IYER V. Clinical pro-file of the SEM Scanner- Modernizing pressure injurycare pathways using sub-epidermal moisture (SEM)scanning [J]. Expert Review of Medical Devices, 2021,18(9): 833-847.
[58] LI A L, SONG J. Biomarkers classification and theirapplication in clinical medicine [J]. Chinese Journal ofPharmacology and Toxicology, 2015, 29(1): 7-13.
[59] SUN M, YANG G, ZHAO Y, et al. Screening of aptamer for breast cancer biomarker calreticulin and itsapplication to detection of serum and recognition ofbreast cancer cell [J]. Chinese Journal of Analytical Chemistry, 2020, 48(5): 642-649 (in Chinese).
[60] BADER D, OOMENS C. The potential of biomarkersin the early detection of pressure ulcers [M]//Scienceand practice of pressure ulcer management. London:Springer, 2018: 1-15.
[61] EDSBERG L E, WYFFELS J T, OGRIN R, et al. Apilot study evaluating protein abundance in pressureulcer fluid from people with and without spinal cordinjury [J]. The Journal of Spinal Cord Medicine, 2015,38(4): 456-467.
[62] SARI Y, NAKAGAMI G, KINOSHITA A, et al.Changes in serum and exudate creatine phosphokinaseconcentrations as an indicator of deep tissue injury:A pilot study [J]. International Wound Journal, 2008,5(5): 674-680.
[63] MINEMATSU T, NAKAGAMI G, SARI Y, et al. Candidate biomarkers for deep tissue damage from molecular biological and biochemical aspects [J]. Journal of Tissue Viability, 2010, 19(2): 77-83.
[64] MAKHSOUS M, PANDYA A, MODI M, et al. Serumand urine biomarker elevation indicating the onset of deep tissue injury as examined on a rat model[C]//ASME 2010 Summer Bioengineering Conference.Naples: ASME, 2010: 807-808.
[65] MAKHSOUS M, LIN F, PANDYA A, et al. Elevationin the serum and urine concentration of injury-relatedmolecules after the formation of deep tissue injury in arat spinal cord injury pressure ulcer model [J]. PM &R,2010, 2(11): 1063-1065.
[66] LOERAKKER S, HUISMAN E S, SEELEN H A M, etal. Plasma variations of biomarkers for muscle damagein male nondisabled and spinal cord injured subjects[J]. Journal of Rehabilitation Research and Development, 2012, 49(3): 361-372.
[67] TRAA W A, STRIJKERS G J, BADER D L, et al.Myoglobin and troponin concentrations are increasedin early stage deep tissue injury [J]. Journal of theMechanical Behavior of Biomedical Materials, 2019,92: 50-57.
[68] SCHWARTZ K, HENZEL M K, ANN RICHMONDM, et al. Biomarkers for recurrent pressure injury riskin persons with spinal cord injury [J]. The Journal ofSpinal Cord Medicine, 2020, 43(5): 696-703.
[69] WYFFELS J T, FRIES K M, RANDALL J S, etal. Analysis of pressure ulcer wound fluid using twodimensional electrophoresis [J]. International WoundJournal, 2010, 7(4): 236-248.
[70] PADULA W V, MALAVIYA S, HU E, et al. Thecost-effectiveness of sub-epidermal moisture scanningto assess pressure injury risk in US health systems [J].Journal of Patient Safety and Risk Management, 2020,25(4): 147-155.