This study aimed to analyze the hemodynamic effects of bifurcated vessels using different bloodviscosity models. Three-dimensional models of bifurcated vessels in the popliteal artery were constructed basedon CT images, and hemodynamic parameters of the Newtonian, Casson, and two-phase models were calculatedby the computational fluid dynamics method. Blood flowed through the popliteal artery. Blood flow velocitychanged after the bifurcated vessel, with accelerated blood flow velocity in the anterior tibial artery. A lowvelocity vortex region with a region of low wall shear stress (WSS) was generated outside the bifurcated vessel.Local non-Newtonian importance factors of great than 1 (i.e., IL > 1) occurred during the cardiac cycle, andIL > 1.75 occurred at the beginning and end of the cycle. Compared with the Casson and two-phase models, theNewtonian model has a larger vortex region and lower WSS. Low-velocity vortex regions and low WSS regionsin the bifurcated vessels may contribute to the development of atherosclerosis. Blood exhibited non-Newtonianfluid properties in bifurcated vessels (IL > 1), and the effect of non-Newtonian properties was more pronouncedat the beginning and end of heartbeats (IL > 1.75). The Newtonian model predicts a higher risk of atherosclerosisformation and the effect of non-Newtonian properties of blood should be considered in hemodynamic studies.
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