Abstract: Novel approaches and instruments to realize noninvasive and in vivo detection to the diseases at early stage are highly demanded. The paper briefly outlines the current detection devices and the developing direction. Some latest methods for detecting malignant tumor on gastrointestinal tract has been used regularly in clinical applications. The detection of relative physiological parameters provides new solution since the diagnosis of functional disorder depends on the parameters. The multiple medical information detection instrument based on microrobots is noninvasive and can be used in vivo. It attracts much attention of researchers on robotics and medical engineering. Finally, the latest trend of this field is predicted.

Key words: gastrointestinal tract diseases, noninvasive detection, wireless capsule endoscopy, microrobot for medical detection on the gastrointestinal tract