上海交通大学学报(自然版)

• 生物医学工程 • 上一篇    下一篇

视觉假体铂铱合金微电极阵列的电场分析

隋晓红a,韩兆龙b,邵轶彬a,周岱b,任秋实a
  

  1. (上海交通大学 a. 生命科学技术学院; b. 船舶海洋与建筑工程学院, 上海 200240)
  • 收稿日期:2009-06-18 修回日期:1900-01-01 出版日期:2010-09-28 发布日期:2010-09-28

Electric Field Analysis of Pt/Ir Microelectrode Array for Visual Prosthesis

SUI Xiaohonga,HAN Zhaolongb,SHAO Yibina,ZHOU Daib,REN Qiushia
  

  1. (a.School of Life Sciences and Biotechnology; b.School of Naval Architecture,
    Ocean and Civil Engineering, Shanghai Jiaotong University, Shanghai 200240, China)
  • Received:2009-06-18 Revised:1900-01-01 Online:2010-09-28 Published:2010-09-28

摘要: 采用有限元法研究用于视神经视觉假体铂铱合金微电极阵列的电场分布情况,在单极和双极电流刺激条件下,分析不同长度微电极的空间电场分布,通过在体动物实验验证了铂铱合金微电极阵列在体工作的有效性.结果表明,经过100 μA的单极和双极电流刺激后,铂铱合金电极的最大电场强度均发生在电极材料和绝缘材料的交界处.以电场强度最大点为原点,单极和双极电流刺激的有效半径分别约为21 和24 μm.

关键词: 铂铱合金(Pt/Ir)微电极, 有限元法, 视神经, 视觉假体, 电场分布

Abstract: Finite element method was employed to simulate the electric field distributions of a Pt/Ir microelectrode array for opticnerve visual prosthesis. Spatial electric field distributions of microelectrodes with different lengths were analyzed under monopolar and bipolar microcurrent excitements. The effectiveness of the Pt/Ir microelectrode array was validated by an experiment on animals. According to the simulation results, when under a 100 μA current stimulation monopolarly and bipolarly, the maximum points of the electric density all locate at the interface of the Pt/Ir material and the insulation. And as the maximum electric field point being the center, the radius of the effective space under monopolar and bipolar stimulations is approximately 21 and 24 μm, respectively.

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