上海交通大学学报

上海交通大学学报 ›› 2019, Vol. 53 ›› Issue (6): 757-764.doi: 10.16183/j.cnki.jsjtu.2019.06.018

• 学报（中文） • 上一篇    

基于剪切稀化效应的血液流体-扩张血管耦合模型的血管损伤分析

江旭东1，李鹏飞1，刘铮1，滕晓艳2   

  1. 1. 哈尔滨理工大学 机械动力工程学院， 哈尔滨 150080； 2. 哈尔滨工程大学 机电工程学院， 哈尔滨 150001
  • 出版日期:2019-06-28 发布日期:2019-07-23
  • 作者简介:江旭东(1977-)，男，吉林省吉林市人，副教授，研究方向为血管支架的非线性力学建模与分析.E-mail：xudongjiang@sina.com.
  • 基金资助:
    国家自然科学基金 (51505096)，黑龙江省自然科学基金 (E2015026)资助项目

Arterial Injury Assessment by Computational Interaction Model of Shear Thinning Blood with Expanded Stenotic Vascular

JIANG Xudong1，LI Pengfei1，LIU Zheng1，TENG Xiaoyan2   

  1. 1. School of Mechanical and Power Engineering, Harbin University of Science and Technology, Harbin 150080, China; 2. College of Mechanical and Electrical Engineering, Harbin Engineering University, Harbin 150001, China
  • Online:2019-06-28 Published:2019-07-23

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摘要： 在考虑血液流体的剪切稀化效应的前提下，分析了人体血管支架、狭窄血管和血液的耦合作用，以及血管支架介入对血管损伤的影响，构建了S型与N型血管支架耦合系统的动力学模型，采用血管的斑块峰值应力、血管壁面的峰值切应力及峰值等效应力等参数来评价斑块易脆性和血管再狭窄等血管的损伤性能.结果表明，与S型支架相比，N型支架的血管斑块峰值应力、血管壁面峰值切应力及其峰值等效应力均较低，能够降低斑块脆性断裂的风险；在N型支架的血管扩张区域的低壁面切应力区域较小且通流截面较大，从而降低了血管再狭窄的发生概率.

关键词: 弯曲血管；血管支架；剪切稀化；血管损伤

Abstract: The interaction of intravascular stent, stenotic artery and blood characterized with shear thinning is analyzed to investigate the induced arterial injury during implantation of a stent into a curved artery. Computational fluid-structure interaction model with S-type and N-type stents is presented to anticipate the plaque vulnerability based on three indices including the peak plaque stress, highest wall shear stress and wall equivalent stress, and the resultant arterial restenosis based on lowest wall shear stress. The numerical results show that the developed peak plaque stress, peak wall shear stress and peak wall equivalent stress for the N-type stent is less than the counterparts for the S-type stent, which suggest that the former takes a lower risk of plaque rupture than the latter. Compared with the S-type stent, the less areas with the lowest wall shear stress and more flow cross-section are observed in the expanded stenotic artery for the N-type stent, which suggests that the risk of arterial restenosis is lower for the N-type stent.

Key words: curved vascular; intravascular stent; shear-thinning; arterial injury

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