In recent years, significant progress has been made through impedance pneumography (IP) in diagnosing pulmonary function. Since there is no need to measure inhalation and exhalation air flow through a pipeline, IP does not increase respiratory resistance and poses no risk of cross-infection, which makes it superior to existing gas flowmeter-based spirometers in clinics. However, the changes in thoracic impedance caused by pulmonary ventilation present significant individual variability. The ratio between pulmonary ventilation volume change (ΔV ) and thoracic impedance change (ΔZ), noted as kΔV/ΔZ , differs among people. IP has to be calibrated for each person by flowmeter-type spirometer before it can be used for quantitative diagnosis. This study aimed to develop a universal model for kΔV/ΔZ using individual parameters such as body height, body mass, body mass index, body fat rate, and chest circumference. The experimental procedure, the way to identify factors for multiple regression via significance analysis and the comparison among different models are presented. This paper demonstrates the possibility of establishing a universal regression model for kΔV/ΔZ , to lay the foundation for the clinical application of IP-based pulmonary function test.
刘恩康1，马艺馨1
,
2，白子轩1，周星1，张明珠1，江泽裔1
. Universal Modeling Method of Electrical Impedance Response During Respiration[J]. Journal of Shanghai Jiaotong University(Science), 2024
, 29(6)
: 967
-978
.
DOI: 10.1007/s12204-023-2593-z
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