Medicine-Engineering Interdisciplinary Research

Time-Resolved Imaging in Short-Wave Infrared Region

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  • (School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China)

Accepted date: 2022-05-21

  Online published: 2024-01-24

Abstract

Compared with the conventional first near-infrared (NIR-I, 700—900 nm) window, the short-wave infrared region (SWIR, 900—1 700 nm) possesses the merits of the increasing tissue penetration depths and the suppression of scattering background, leading to great potential for in vivo imaging. Based on the limitations of the common spectral domain, and the superiority of the time-dimension, time-resolved imaging eliminates the auto-fluorescence in the biological tissue, thus supporting higher signal-to-noise ratio and sensitivities. The imaging technique is not affected by the difference in tissue composition or thickness and has the practical value of quantitative in vivo detection. Almost all the relevant time-resolved imaging was carried out around lanthanide-doped upconversion nanomaterials, owing to the advantages of ultralong luminescence lifetime, excellent photostability, controllable morphology, easy surface modification and various strategies of regulating lifetime. Therefore, this review presents the research progress of SWIR time-resolved imaging technology based on nanomaterials doped with lanthanide ions as luminescence centers in recent years.

Cite this article

XU Yang (徐杨), LI Wanwan∗ (李万万) . Time-Resolved Imaging in Short-Wave Infrared Region[J]. Journal of Shanghai Jiaotong University(Science), 2024 , 29(1) : 29 -36 . DOI: 10.1007/s12204-022-2547-x

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