Biochemical reaction in microfluidic chip is sensitive to temperature. Temperature precise control in
a small size device requires the temperature measurement with high measurement precision. Traditional temperature
measurement method usually measures the voltage drop of the thermistor, which is excited by a constant
current source. This method requires the constant current source with high precision and stability. The output
of the constant current source is influenced by environmental factors, resulting in a larger measurement error. To
solve this problem, a proportion method, a two-layer filtering algorithm, and a power management technique were
applied to improve the temperature measurement precision. The proportion method can reduce the low frequency
fluctuation error. The two-layer filtering algorithm can reduce the high frequency fluctuation error further. The
power management technique used can improve the system stability. Through testing the temperature measurement
system built, the experimental results show that the fluctuation error can be significantly decreased from
0.5 ?C to 0.2?C.
XIONG Yuefu (熊越夫), WU Xiaosheng∗ (吴校生), ZENG Zhaofeng (曾照丰),
HUANG Shan (黄山), CHEN Tianpei (陈天培)
. High Precision Temperature Measurement for Microfluidic Chip Applications[J]. Journal of Shanghai Jiaotong University(Science), 2022
, 27(5)
: 699
-705
.
DOI: 10.1007/s12204-021-2370-9
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