Design of Real-Time Temperature Monitoring and Control System for Multimodal Ablation

doi:10.1007/s12204-022-2432-7

摘要/Abstract

Abstract: By combining cryogenic cryotherapy and high-temperature radiofrequency therapy, multimodal abla- tion generates a rapidly changing temperature field in tissue by heating after pre-freezing. This method completely breaks tumour cells and releases a large amount of active antigen. Compared with the traditional single modal- ity, the thermal physical ablation method has been shown to have a greater therapeutic effect, but it presents challenges in terms of precise monitoring and rapid control of the temperature during the treatment process. To solve this problem, we propose a temperature control system design utilizing aspects of probe sensing, real- time software and hardware signal interfaces, and dynamic compensation control strategies to accurately monitor the temperature changes during multimodal ablation treatment. The results show that the design system has millisecond-level high-speed control capability, an accuracy of 0.5 ?C, and the dynamic response time is less than 0.1 s. Furthermore, the temperature fluctuation in in vivo e x p e r i m e n t s i s l e s s t h a n 0 . 5 ?C.

Key words: ablation, temperature monitor, system design

中图分类号:

TH772

. [J]. J Shanghai Jiaotong Univ Sci, 2022, 27(4): 535-542.

ZOU Ke (邹柯), ZOU Jincheng (邹金成), WANG Yifei (王逸飞), ZHANG Aili ∗ (张爱丽). Design of Real-Time Temperature Monitoring and Control System for Multimodal Ablation[J]. J Shanghai Jiaotong Univ Sci, 2022, 27(4): 535-542.

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