It is a common problem that the glass panel falls due to the damage of silicone structural sealant used for the connection of the hidden frame glass curtain walls in the service life of the curtain walls. Most of the existing studies used dynamics methods to detect the debonding damage of curtain walls. However, these methods usually require additional load excitation, and the measured dynamic response data are susceptible to environmental noise, which makes it difficult to achieve reliable assessment of the safety condition of curtain walls. In order to solve the above problems, this paper proposes a method to detect the debonding damage of curtain wall units by using the deflection and rotation angles of the glass panel under the action of negative wind pressure. First, a series of debonding damage experiments of hidden frame glass curtain wall are designed to verify the feasibility of using deflection and rotation angle to detect the safety state of the curtain wall under wind load. Then, based on the experimental results, a safety risk monitoring system for hidden frame glass curtain walls is proposed, which can realize the real-time monitoring of curtain wall units and conduct rapid ide.pngication of debonding damage.