In order to explore the wake characteristics of non-ducted and ducted propellers in oblique inflow with a large drift angle, based on the delayed detached eddy simulation, a numerical simulation of non-ducted and ducted propellers in oblique inflow is conducted with an advance coefficient (J=0.4) and a large drift angle (β=45°, 60°). It is found that the deflection degree of the non-ducted propeller wake is higher than that of the ducted propeller. However, the overall distribution area of the wake vortex behind the ducted propeller is kinked. The wake field in the oblique flow shows its complexity, and the evolution process of vortices on the windward side differs from that on the leeward side. The above characteristic of the non-ducted propeller is more prominent. At the same time, the leading edge of the nozzle on the leeward side will produce local shedding vortices and transmit to the downstream due to flow separation. Part of the kinetic energy of the ducted propeller is converted into the nozzle thrust, which makes the turbulence kinetic energy of the wake lower than that of the non-ducted propeller. This phenomenon is more evident with the increase in the drift angle. Compared with the non-ducted propeller, the ducted propeller can maintain a better handling stability in large-angle oblique flow. This paper analyzes the influence of large-angle oblique inflow on the non-ducted and ducted propellers from the perspective of wake field characteristics and explores the theoretical basis for the ducted propeller to maintain a better handling stability in oblique flow.