Aimed at the problem of weak coordination and low balance of distributed resources under multiple parallel deicing tasks, a cooperative control method of aircraft ground deicing resources based on multi-agent negotiation was proposed, which combined airport deicing resource allocation and space-time distribution. A framework for collaborative operation of multi-agent deicing resources was established, and a resource optimization method for the bidding mechanism of a global collaborative consortium was designed to improve the overall task balance. Based on the operating plan, an autonomous multi-agent resource collaborative optimization model was constructed. The model predictive control method was applied to generate a collaborative control strategy, and the feasibility was verified in actual scenarios. The results demonstrate that the resource coordination and anti-interference ability of the proposed method are significantly enhanced while meeting the real-time requirements. Compared with the results obtained by other methods, the average takeoff tolerance is 4.89 min, increased by 1.015 min, and the average utilization rate is increased by 15.28%, which can ensure the safety and synergy of deicing resources.