By considering the smallest feature that can be observed by an optical microscope, the development of optical microscopy and the efforts made to break the diffraction limit were reviewed. Optical microscopy is crucial for science at small scales. Although the diffraction limit has been overcome, the continuous effort made in this field would enable a further improvement in resolution.
WANG Tiesheng
. How Small an Object Can Be Observed by an Optical Microscope?[J]. Journal of Shanghai Jiaotong University, 2021
, 55(Sup.1)
: 110
-111
.
DOI: 10.16183/j.cnki.jsjtu.2021.S1.050
[1]ZHELUDEV N I. What diffraction limit?[J]. Nature Materials, 2008, 7(6): 420-422.
[2]李明. 超分辨显微, 至极至美: 2014年诺贝尔化学奖述评[J]. 物理, 2014, 43(12): 813-816.
LI Ming. Beyond the limit: Super-resolution microscopy earned the Nobel Prize in Chemistry 2014[J]. Physics, 2014, 43(12): 813-816.
[3]RSNER B, FINIZIO S, KOCH F, et al. Soft X-ray microscopy with 7 nm resolution[J]. Optica, 2020, 7(11): 1602-1608.