Journal of Shanghai Jiao Tong University

Journal of Shanghai Jiaotong University

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Isolation and Structural Identification of a Tetraene Macrolide Produced by Streptomyces hygrospinosus var. Beijingensis

YAO Fen1，KANG Qianjin1，LIN Shuangjun1，ZHU Changxiong2，
YOU Delin1，DENG Zixin1
  

  1. (1.School of Life Sciences and Biotechnology, Shanghai Jiaotong University, Shanghai 200240, China；
    2.Institute of Environment and Sustainable Development in Agriculture,
    Chinese Academy of Agricultural Sciences, Beijing 100081, China)
  • Received:2010-04-06 Revised:1900-01-01 Online:2011-01-27 Published:2011-01-27

Abstract: A tetraene compound was purified from the secondary metabolites of Streptomyces hygrospinosus var. Beijingensis, the producing strain of Agroantibiotic 120. The results of LCMS on molecular weight and NMR on structural identification show that it is Tetramycin B with the UV absorption spectrum of tetraene macrolide antibiotics. The bioassay result shows it inhibits the growth of Saccharomyces cerevisiae, indicating it is one of the effective components in Agroantibiotic 120.

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