Abstract: This paper proposed a frequency domain nonsubsampled contourlet transform (FNSCT) algorithm accelerated by graphic processing unit (GPU). This approach builds a simple and highspeed nonsubsampled contourlet transform in frequency domain to eliminate the ringing and pseudoGibbs phenomena caused by wavelet or contourlet transformation. Also it accelerates the time domain nonsubsampled contourlet transform (NSCT) algorithm with the help of GPU to achieve a high speed and accuracy medical image fusion method.