上海交通大学学报 ›› 2021, Vol. 55 ›› Issue (Sup.1): 53-54.doi: 10.16183/j.cnki.jsjtu.2021.S1.042

所属专题: 上海交通大学建校125周年科学问题专辑

• 医学科学 • 上一篇    下一篇

免疫治疗能否治愈肿瘤?

宗春燕,沈键锋   

  1. 上海交通大学医学院附属第九人民医院 眼科; 上海市眼眶病眼肿瘤重点实验室, 上海 200025
  • 收稿日期:2021-02-03 出版日期:2021-03-28 发布日期:2021-04-09
  • 通讯作者: 沈键锋,男,研究员,博士生导师,电话(Tel.):021-53314246;E-mail:jfshen@shsmu.edu.cn.
  • 作者简介:宗春燕(1996-),女,江苏省南通市人,硕士生,从事眼肿瘤方面的研究.
  • 基金资助:
    国家自然科学基金(81972667),上海市东方学者(TP2018046)资助项目

Can Immunotherapy Cure Cancer?

ZONG Chunyan,SHEN Jianfeng   

  1. Department of Ophthalmology; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
  • Received:2021-02-03 Online:2021-03-28 Published:2021-04-09

摘要: 随着免疫检查点抑制剂、肿瘤疫苗、过继性细胞免疫疗法等肿瘤免疫治疗技术的飞速发展,免疫治疗已展现出相较于传统肿瘤治疗方法的巨大优势.本文简述了当前肿瘤免疫治疗存在的问题,并就免疫能否全面改变肿瘤治疗现状,甚至彻底治愈肿瘤这一问题展开论述.

关键词: 肿瘤免疫治疗;免疫检查点抑制剂;肿瘤疫苗;过继性细胞免疫疗法

Abstract: With the rapid development of therapeutics such as immune checkpoint blockade, tumor vaccines, and adoptive cellular immunotherapy, cancer immunotherapy has demonstrated significant advantages over traditional treatment methods. This paper briefly introduces the challenges in the current cancer immunotherapy, and discusses herein whether immunotherapy could lead to the paradigm shift of cancer therapy or even cure cancer.

Key words: immunotherapy; immune checkpoint blockade; tumor vaccine; adoptive cellular immunotherapy

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