上海交通大学学报 ›› 2021, Vol. 55 ›› Issue (Sup.1): 16-17.doi: 10.16183/j.cnki.jsjtu.2021.S1.025

所属专题: 上海交通大学建校125周年科学问题专辑

• 生命科学 • 上一篇    下一篇

如何获得大量的造血干细胞?

董了了,程林   

  1. 上海交通大学医学院附属瑞金医院 上海血液学研究所;医学基因组学国家重点实验室;转化医学国家重大科技基础设施(上海), 上海 200025
  • 收稿日期:2021-02-03 出版日期:2021-03-28 发布日期:2021-04-09
  • 通讯作者: 程林,男,研究员,博士生导师,电话(Tel.):021-64370045-610808;E-mail:lincheng@shsmu.edu.cn.
  • 作者简介:董了了(1998-),女,浙江省台州市人,硕士生,从事造血干细胞研究.
  • 基金资助:
    国家自然科学基金(92068101,31871498),上海市高峰高原计划(828313)资助项目

How to Get a Large Number of Hematopoietic Stem Cells?

DONG Liaoliao,CHENG Lin   

  1. Shanghai Institute of Hematology; State Key Laboratory of Medical Genomics; National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
  • Received:2021-02-03 Online:2021-03-28 Published:2021-04-09

摘要: 简要介绍了造血干细胞的基础研究和临床应用价值,指出大量造血干细胞的获得是亟待解决的重要科学问题.造血干细胞扩增和诱导产生造血干细胞是极具前景的研究方向,同时面临多重机遇和挑战.

关键词: 造血干细胞;扩增;分化;重编程

Abstract: This paper briefly introduces the basic research and clinical application value of hematopoietic stem cells and points out that acquiring a large number of hematopoietic stem cells is an important scientific problem to be solved urgently. Expansion and induction of hematopoietic stem cells is a promising research direction, which faces multiple opportunities and challenges.

Key words: hematopoietic stem cell; expansion; differentiation; reprogramming

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