上海交通大学学报 ›› 2021, Vol. 55 ›› Issue (Sup.1): 14-15.doi: 10.16183/j.cnki.jsjtu.2021.S1.024

所属专题: 上海交通大学建校125周年科学问题专辑

• 生命科学 • 上一篇    下一篇

单细胞生命体的系统工作原理是什么?

丁显廷   

  1. 上海交通大学 生物医学工程学院; 个性化医学研究院, 上海 200030
  • 收稿日期:2021-02-03 出版日期:2021-03-28 发布日期:2021-04-09
  • 通讯作者: 丁显廷(1984-),男,上海市人,教授,博士生导师,从事单细胞蛋白检测及临床应用. 电话(Tel.):021- 62932274;E-mail:dingxianting@sjtu.edu.cn.
  • 基金资助:
    国家自然科学基金(81871448, 22077079)资助项目

What Is Functioning Machinery of SingleCell Organism?

DING Xianting   

  1. School of Biomedical Engineering; Institute for Personalized Medicine, Shanghai Jiao Tong University, Shanghai 200030, China
  • Received:2021-02-03 Online:2021-03-28 Published:2021-04-09

摘要: 世界上许多的单细胞生命体以高效率和高准确性在运行着.比如一个巨噬细胞可以实时地动态追踪一个细菌,说明这种单细胞生物的感知器和控制器都是异常精密和发达的.人类目前尚未了解单细胞生命体的运行规律.破译这一科学问题,将对仿生机器人、新的系统调控原理、控制理论、蛋白质网络、新药研发、细胞衰老等众多领域都具有重大的价值.

关键词: 单细胞生命体;生物医学工程;仿生机器人;复杂系统;控制理论

Abstract: Many single-cell organisms function with extraordinary efficiency and accuracy. For example, a macrophage can track a bacterial dynamically in real time, which indicates that such single-cell organism has extraordinary advanced sensors and actuators. It remains unknown for human beings how such delicate single-cell organisms operate. Understanding this fundamental scientific hurdle is of great value to many fields, such as bio-mimic robotics, control theory, protein networking, drug development, cell aging, etc.

Key words: single-cell organism; biomedical engineering; bio-mimic robotics; complex system; control theory

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