用于电刺激人造视网膜系统的专用集成电路设计

doi:10.16183/j.cnki.jsjtu.2018.10.011

上海交通大学学报（自然版） ›› 2018, Vol. 52 ›› Issue (10): 1234-1241.doi: 10.16183/j.cnki.jsjtu.2018.10.011

用于电刺激人造视网膜系统的专用集成电路设计

陈曦,周杰,郭训华,郑志恒,李慧,陈诚,王国兴

上海交通大学微纳电子学系，上海 200240

通讯作者: 王国兴，男，副教授，博士生导师，电话(Tel.): 021-34204546—1070; E-mail: guoxing@sjtu.edu.cn.
作者简介:陈曦(1990-)，男，北京市人，博士研究生，主要研究方向为人造视网膜.
基金资助:
广东省引进创新团队计划资助项目(2013S046)，深圳海外高层次人才资金资助项目

Integrated Circuit Design for Retinal Prosthesis System

CHEN Xi,ZHOU Jie,GUO Xunhua,ZHENG Zhiheng

Department of Micro/Nano Electronics, Shanghai Jiao Tong University, Shanghai 200240, China

摘要/Abstract

摘要： 老年性黄斑变性(Age-related Macular Degeneration, AMD)及视网膜色素变性(Retinitis Pigmentosa, RP)是视网膜退化及致盲的常见原因.研究发现，这些患者视网膜中的大部分神经细胞及视神经通路依旧完好，借助人造视网膜的电刺激有可能恢复患者的视觉.专用集成电路是人造视网膜系统中最关键的组成部分.介绍了人造视网膜系统中专用集成电路的发展，并提出了用于新一代高密度电刺激人造视网膜系统的专用集成电路体系架构，同时设计并测试了采用此体系架构的一款128通道的专用芯片.

关键词: 人造视网膜, 专用集成电路

Abstract: Retina degenerations including age-related macular degeneration (AMD) and retinitis pigmentosa (RP) are common diseases causing blindness. Studies show that although the photo receptors in patients’ retina are damaged, most of the vision neurons remain attached, making current stimulation possible to restore vision. Application specific integrated circuit (ASIC) plays an important role in the development of retinal prosthesis. In this paper, the development of ASIC in retinal prosthesis is firstly reviewed. Architecture and chip designs of an ASIC for 128-channel retinal prosthesis are then introduced and the test results are presented.

Key words: retinal prosthesis, application specific integrated circuits (ASIC)

中图分类号:

TN 492

陈曦,周杰,郭训华,郑志恒,李慧,陈诚,王国兴. 用于电刺激人造视网膜系统的专用集成电路设计[J]. 上海交通大学学报（自然版）, 2018, 52(10): 1234-1241.

CHEN Xi,ZHOU Jie,GUO Xunhua,ZHENG Zhiheng. Integrated Circuit Design for Retinal Prosthesis System[J]. Journal of Shanghai Jiaotong University, 2018, 52(10): 1234-1241.

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