上海交通大学学报

上海交通大学学报 ›› 2021, Vol. 55 ›› Issue (Sup.1): 30-31.doi: 10.16183/j.cnki.jsjtu.2021.S1.032

所属专题： 上海交通大学建校125周年科学问题专辑

• 生命科学 • 上一篇    下一篇

人为什么会老化——生物体的老化机制

刘泽，杨国源   

  1. 上海交通大学 生物医学工程学院，上海 200030
  • 收稿日期:2021-02-03 出版日期:2021-03-28 发布日期:2021-04-09
  • 通讯作者: 杨国源，男，教授，博士生导师，电话(Tel.): 13024189121；E-mail: gyyang@sjtu.edu.cn.
  • 作者简介:刘泽(1997-)，女，江苏省宿迁市人，硕士生，从事老化和脑科学研究.

Why Do People Age: Aging Mechanism of Organism

LIU Ze,YANG Guoyuan   

  1. School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China
  • Received:2021-02-03 Online:2021-03-28 Published:2021-04-09

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摘要： 衰老问题无法回避，也是困扰科学家们多年的难题.人类衰老的现代主流生物学理论主要分为程序化理论、损伤或误差理论两大类.随着医学水平的不断提高，微循环理论、端粒酶学说等多种新型的衰老学说不断涌现，丰富了该领域的研究视角.但现有理论仍不能较好地解释衰老过程，并就这一问题达成共识，同时许多理论以一种复杂的方式相互关联.理解和检验各种老龄化理论，可以促进人类对衰老机制的理解，并造福于人类.

关键词: 衰老；寿命；机制

Abstract: Aging is an unavoidable problem that has puzzled scientists for years. The programming theory and the damage or error theory are representatives of the modern mainstream biological theories on human aging. With the continuous improvement of medicine, a variety of novel aging theories such as the microcirculation theory and the telomerase theory have emerged, which enrich the research perspectives in this field. But the existing theories are still not good enough to explain the process of aging. Many theories are related to each other in a complex way. The research and test of various aging theories can promote the understanding of the aging mechanism and benefit human beings.

Key words: aging; lifespan; mechanism

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