In this paper, a numerical simulation of flow-induced noise by the low Mach number turbulent flow with a sinusoidal wavy wall was presented based on the unsteady incompressible Navier-Stokes equations and Lighthill's acoustic analogy. Large eddy simulation (LES) was used to investigate the space-time flow field and the Smagorinsky sub-grid scale (SGS) model was introduced for turbulence model. Using Lighthill's acoustics analogy, the flow field simulated by LES was taken as near-field sound sources and radiated sound from turbulent flow was computed by the Curle's integral formulation under the low Mach number approximation. Both spanwise wavy wall and streamwise wavy wall with various wall wave amplitudes were discussed to investigate their effects on reducing the drag and flow noise. The relationship between flow noise and drag on the wavy wall is also studied. © 2011 Shanghai Jiaotong University and Springer-Verlag Berlin Heidelberg.