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Optimization Design of Flexible Neural Electrodes Based on Orthogonal Experimental Method
Received date: 2019-03-14
Online published: 2020-08-18
In order to optimize the design of flexible neural electrodes, three parameters of elastic modulus, electrode thickness, and wedge angle are comprehensively studied. The experimental groups are established based on orthogonal experimental design. The maximum strain of brain tissue in different experimental groups are evaluated by ANSYS. In addition, a new hybrid flexible electrode is designed based on the stimulation results. The experimental results reveal that when elastic modulus is 8.5GPa, thickness is 15μm and wedge angle is 45°, the maximum strain of brain tissue due to micromotion is the smallest, i.e., 5.5627×10-2. Moreover, a sandwich-type hybrid flexible neural electrode is designed with an elastic modulus of 8.5GPa on both sides and an elastic modulus of 5.5GPa in the intermediate layer. The sandwich-type structure can effectively reduce micromotion damage and implant deformation compared to the traditional electrode.
XIE Jie, ZHANG Wenguang, YIN Xuele, LI Wei . Optimization Design of Flexible Neural Electrodes Based on Orthogonal Experimental Method[J]. Journal of Shanghai Jiaotong University, 2020 , 54(8) : 785 -791 . DOI: 10.16183/j.cnki.jsjtu.2019.068
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