医学科学

免疫治疗能否治愈肿瘤?

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  • 上海交通大学医学院附属第九人民医院 眼科; 上海市眼眶病眼肿瘤重点实验室, 上海 200025
宗春燕(1996-),女,江苏省南通市人,硕士生,从事眼肿瘤方面的研究.

收稿日期: 2021-02-03

  网络出版日期: 2021-04-09

基金资助

国家自然科学基金(81972667),上海市东方学者(TP2018046)资助项目

Can Immunotherapy Cure Cancer?

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  • Department of Ophthalmology; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

Received date: 2021-02-03

  Online published: 2021-04-09

摘要

随着免疫检查点抑制剂、肿瘤疫苗、过继性细胞免疫疗法等肿瘤免疫治疗技术的飞速发展,免疫治疗已展现出相较于传统肿瘤治疗方法的巨大优势.本文简述了当前肿瘤免疫治疗存在的问题,并就免疫能否全面改变肿瘤治疗现状,甚至彻底治愈肿瘤这一问题展开论述.

本文引用格式

宗春燕,沈键锋 . 免疫治疗能否治愈肿瘤?[J]. 上海交通大学学报, 2021 , 55(Sup.1) : 53 -54 . DOI: 10.16183/j.cnki.jsjtu.2021.S1.042

Abstract

With the rapid development of therapeutics such as immune checkpoint blockade, tumor vaccines, and adoptive cellular immunotherapy, cancer immunotherapy has demonstrated significant advantages over traditional treatment methods. This paper briefly introduces the challenges in the current cancer immunotherapy, and discusses herein whether immunotherapy could lead to the paradigm shift of cancer therapy or even cure cancer.

参考文献

[1]HONG M H, CLUBB J D, CHEN Y Y. Engineering CAR-T cells for next-generation cancer therapy[J]. Cancer Cell, 2020, 38(4): 473-488. [2]BRAUN D A, BAKOUNY Z, HIRSCH L, et al. Beyond conventional immune-checkpoint inhibition: Novel immunotherapies for renal cell carcinoma[J/OL]. Nature Reviews Clinical Oncology, 2021. [2021-02-03]. https:∥doi.org/10.1038/s41571-020-00455-z.
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