生物具有显著的可塑性，在组织损伤后可有效再生和重建稳态.当再生信号被异常激活时，该细胞可塑性将促进肿瘤发生.组织再生和肿瘤发生均依赖于组织水平上多形式细胞可塑性的协调整合，因此对其机制的认识有助于损伤修复和肿瘤防治.

Organism is characterized by a remarkable plasticity, which drives efficient regeneration and restoration of homeostasis after damage. When aberrantly activated, this plasticity contributes to tumor initiation and progression. Both regenerative and tumorigenic processes rely on the coordinated integration at the tissue level of multiple forms of cellular plasticity. Understanding the mechanisms underlying the various forms of cell plasticity may deliver novel strategies for developing regenerative therapies, cancer prevention, and antitumor treatments.